Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 187
interventional 140
Observational 43
Registry 4

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 35
Drug|placebo 27
Behavioral 22
Other 17
Device 10
Procedure 6
Behavioral|Other 3
Behavioral|placebo 3
Behavioral|Drug|placebo 2
Dietary Supplement|placebo 2
Drug|Other 2
Drug|Procedure 2
Other|placebo 2
Behavioral|Biological|Other 1
Behavioral|Drug 1
Biological 1
Combination Product 1
Dietary Supplement 1
Dietary Supplement|Drug 1
Radiation 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 70
France 10
NA 10
Canada 6
China 5
Spain 5
Denmark 3
Netherlands 3
United Kingdom 3
Croatia 2
Germany 2
Italy 2
Norway 2
Russian Federation 2
Taiwan 2
Australia 1
Belgium|Israel|Italy|Netherlands|United Kingdom 1
Denmark|Italy|Netherlands|Sweden|United Kingdom 1
Hong Kong 1
Ireland 1
Korea, Republic of 1
New Zealand 1
Poland 1
Turkey 1
Uganda 1
United States|Australia|Canada|Japan 1
United States|China|Israel 1
United States|Russian Federation|United Kingdom 1

Sites per Study

Site_count Study_Count
1 100
2 14
3 6
4 3
5 3
7 1
8 1
12 2
15 2
20 2
23 1
24 2
30 1
61 1
68 1

Phase

Phase Study_Count
N/A 73
Phase 2 21
Phase 4 17
Phase 1 13
Phase 3 9
Early Phase 1 3
Phase 1/Phase 2 2
Phase 2/Phase 3 2

Number of Arms

Number_of_Arms Count_of_Studies
1 21
2 64
3 22
4 12
5 1
9 1
NA 19

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 32.00000 6.0000 4.00000 17.00 10.0000 21.00 40.000 8.0000
1st Qu. 32.00000 44.0000 24.00000 27.75 34.0000 36.25 97.500 60.0000
Median 32.00000 90.0000 30.00000 38.50 80.0000 51.50 162.500 80.0000
Mean 61.33333 132.8082 36.30769 38.50 110.2857 51.50 334.375 809.7647
3rd Qu. 76.00000 150.0000 50.00000 49.25 150.0000 66.75 365.500 121.0000
Max. 120.00000 1635.0000 72.00000 60.00 432.0000 82.00 1150.000 10000.0000

Trial Group Type

group_type Group_Count
Experimental 137
Active Comparator 57
Placebo Comparator 46
NA 19
No Intervention 17
Other 13
Sham Comparator 7

Intervention Model

intervention_model Study_Count
Parallel Assignment 92
Single Group Assignment 25
Crossover Assignment 14
NA 5
Factorial Assignment 3
Sequential Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 86
Prevention 15
Diagnostic 10
Other 9
Supportive Care 8
NA 7
Basic Science 4
Health Services Research 1

Observational Studies

Studies by Country

Country Study_Count
United States 16
NA 4
France 3
Switzerland 3
Canada 2
China 2
Argentina 1
Australia|Germany|Spain|Sweden 1
Austria 1
Cyprus 1
Denmark 1
Denmark|Sweden|United Kingdom 1
Germany 1
Greece 1
Norway 1
Russian Federation 1
Spain 1
United States|Puerto Rico 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 30
2 4
3 1
4 2
6 1
8 1
21 1
25 1
26 1
41 1

Enrollment Metrics

Measure Observational
Min 1.0000
1st Qu 101.5000
Median 230.0000
Mean 517.7209
3rd Qu 487.5000
Max 2920.0000

Observation Model

observational_model Study_Count
Cohort 22
NA 5
Other 4
Case-Control 3
Case-Only 3
Case-Crossover 2
Case Control 2
Ecologic or Community 1
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 33
Cross-Sectional 4
NA 4
Retrospective 2

Registries

Studies by Country

Country Study_Count
Germany 1
Hong Kong 1
Italy 1
United States 1

Sites per Study

Site_count Study_Count
1 3
75 1

Enrollment Metrics

Measure Registries
Min 132.00
1st Qu 215.25
Median 274.00
Mean 249.25
3rd Qu 308.00
Max 317.00

Registry Model

observational_model Study_Count
Case-Control 2
Cohort 1
Other 1

Time Perspective

time_perspective Study_Count
Cross-Sectional 2
Other 1
Prospective 1

Follow-up

target_duration Study_Count
2 Days 1
2 Years 1
5 Years 1
6 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03368482 Brain Gym® Exercises for Institutionalized Elderly People With Cognitive Impairment https://ClinicalTrials.gov/show/NCT03368482 Completed University of Vigo 2015-03-01
NCT03342989 Speed of Processing Training for Cognitive Deficits After Delirium in Older Adults https://ClinicalTrials.gov/show/NCT03342989 Recruiting University of Alabama at Birmingham 2022-09-30
NCT03299855 MoCA vs. MMS: Which Tool to Detect Cognitive Disorders in Oncogeriatric? https://ClinicalTrials.gov/show/NCT03299855 Recruiting Centre Francois Baclesse 2022-04-30
NCT03205709 Cognitive Training and Neuroplasticity in Mild Cognitive Impairment https://ClinicalTrials.gov/show/NCT03205709 Recruiting New York State Psychiatric Institute 2022-07-31
NCT03194074 Early Cognitive Function in Elderly Patients After Laser Laryngeal Surgery: Des vs Prop https://ClinicalTrials.gov/show/NCT03194074 Recruiting Eye & ENT Hospital of Fudan University 2019-06-30
NCT03122288 Individualized Cognitive Training in HIV https://ClinicalTrials.gov/show/NCT03122288 Completed University of Alabama at Birmingham 2019-02-27
NCT03094312 Evaluation of the Risk of Cognitive Deficit After Surgery of Epilepsy by Dynamic Spectral Imaging (ISD) of the Cognitive Functions in Patients Explored in StereoElectroEncephaloGraphy (SEEG) https://ClinicalTrials.gov/show/NCT03094312 Recruiting Hospices Civils de Lyon 2022-01-23
NCT03093142 The Treatment Effectiveness of Combined tDCs and Neurofeedback (NF) for Patients With Cognitive Deficits After Stroke https://ClinicalTrials.gov/show/NCT03093142 Recruiting Kowloon Hospital, Hong Kong 2019-09-30
NCT03061006 Impact of Anticoagulation Therapy on the Cognitive Decline and Dementia in Patients With Non-Valvular Atrial Fibrillation https://ClinicalTrials.gov/show/NCT03061006 Recruiting Intermountain Health Care, Inc. 2021-04-30
NCT03054857 The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac Surgery https://ClinicalTrials.gov/show/NCT03054857 Completed Chulalongkorn University 2016-12-31
NCT03037879 Treating Cognitive Deficits in Spinal Cord Injury https://ClinicalTrials.gov/show/NCT03037879 Recruiting James J. Peters Veterans Affairs Medical Center 2020-01-31
NCT03031574 A Study to Investigate the Effect of Food, Gender, and Age on the Pharmacokinetic Profile of SUVN-D4010 in Healthy Subjects https://ClinicalTrials.gov/show/NCT03031574 Completed Suven Life Sciences Limited 2017-08-29
NCT02957123 Intranasal Inhalations of Bioactive Factors Produced by M2 Macrophages in Patients With Organic Brain Syndrome https://ClinicalTrials.gov/show/NCT02957123 Recruiting Russian Academy of Medical Sciences 2020-11-30
NCT02918461 Emerging From the Haze for Gynecologic Cancer Survivors https://ClinicalTrials.gov/show/NCT02918461 Completed Cedars-Sinai Medical Center 2017-05-31
NCT02881294 A Study to Investigate the Effect of Food, Gender, and Age on the Pharmacokinetic Profile of SUVN-G3031 in Healthy Subjects https://ClinicalTrials.gov/show/NCT02881294 Completed Suven Life Sciences Limited 2017-09-30
NCT02850146 18F-AV-1451 PET Imaging in Participants Enrolled in the LEARN Study https://ClinicalTrials.gov/show/NCT02850146 Active, not recruiting University of Southern California 2020-06-30
NCT02847793 Attentional Bias Modification Through Eye-tracker Methodology (ABMET) https://ClinicalTrials.gov/show/NCT02847793 Completed Universidad Complutense de Madrid 2017-04-01
NCT02816008 Smart Autonomous Neuro-Rehabilitation System https://ClinicalTrials.gov/show/NCT02816008 Completed Universitat Pompeu Fabra 2018-02-28
NCT02813434 Cerebral Amyloid Imaging Using Florbetapir (AV-45) https://ClinicalTrials.gov/show/NCT02813434 Recruiting Centre Hospitalier Universitaire, Amiens 2022-09-30
NCT02761330 Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia https://ClinicalTrials.gov/show/NCT02761330 Completed Washington University School of Medicine 2019-09-11
NCT02748083 Transcranial Direct Current Stimulation (tDCS) as a Treatment for Cognitive Deficits in Schizophrenic https://ClinicalTrials.gov/show/NCT02748083 Completed Shanghai Mental Health Center 2017-09-01
NCT02680210 Self-defining Memories in Patients With a TBI https://ClinicalTrials.gov/show/NCT02680210 Completed Centre d’Investigation Clinique et Technologique 805 2016-05-31
NCT02575482 A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-D4010 in Healthy Subjects https://ClinicalTrials.gov/show/NCT02575482 Completed Suven Life Sciences Limited 2016-02-29
NCT02574234 Influence of Apelin Levels on Postoperative Cognitive Disorders After Orthopedic Surgery in Elderlies (APOCOGNIT) https://ClinicalTrials.gov/show/NCT02574234 Completed University Hospital, Toulouse 2018-03-31
NCT03095170 Physical Exercise And Cognitive Engagement Outcomes for Mild Neurocognitive Disorder https://ClinicalTrials.gov/show/NCT03095170 Recruiting University of Florida 2021-06-30
NCT02035436 Non-sedation Versus Sedation With a Daily Wake-up Trial in Critically Ill Patients Receiving Me-chanical Ventilation - Effects on Cognitive Function https://ClinicalTrials.gov/show/NCT02035436 Completed Odense University Hospital 2017-06-30
NCT02554253 The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction https://ClinicalTrials.gov/show/NCT02554253 Active, not recruiting Mayo Clinic 2020-12-31
NCT02505477 Treatment of Cognitive and Negative Symptoms in Schizophrenia With N-acetylcysteine https://ClinicalTrials.gov/show/NCT02505477 Recruiting University of California, Los Angeles 2020-01-31
NCT02342236 Cerebral Regional Oxygen Saturation and Markers of Brain Damage During Primary Hip Arthroplasty https://ClinicalTrials.gov/show/NCT02342236 Completed Military Institute of Medicine, Poland 2015-12-31
NCT02342041 A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-G3031 in Healthy Subjects https://ClinicalTrials.gov/show/NCT02342041 Completed Suven Life Sciences Limited 2015-06-30
NCT02292316 Falls With Fracture : Role of Cognitive Disorders and Comparison With Bone Fragility https://ClinicalTrials.gov/show/NCT02292316 Completed University Hospital, Caen 2017-12-31
NCT02265757 Behavioral Interventions to Prevent or Delay Dementia https://ClinicalTrials.gov/show/NCT02265757 Completed Mayo Clinic 2018-03-31
NCT02225106 Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI https://ClinicalTrials.gov/show/NCT02225106 Completed University of Pennsylvania 2017-06-21
NCT02214342 Virtual Reality Based Balance Training in People With Mild Cognitive Impairment https://ClinicalTrials.gov/show/NCT02214342 Completed University of Arizona 2014-09-30
NCT02197104 Citocoline for Treatment of FXTAS https://ClinicalTrials.gov/show/NCT02197104 Completed Rush University Medical Center 2017-01-31
NCT02141022 Computerized Exercise Training for Cognitive Remediation in Adults With Multiple Sclerosis Treated With Gilenya https://ClinicalTrials.gov/show/NCT02141022 Completed Stony Brook University 2014-09-30
NCT02136953 Physical Exercise in OCD: Treatment Efficacy, Additive Benefits to CBT, and Cognitive Correlates of Change https://ClinicalTrials.gov/show/NCT02136953 Completed Sunnybrook Health Sciences Centre 2017-10-31
NCT02128919 Transcranial Direct Current Stimulation (tDCS) As A Treatment For Cigarette Craving and Cognitive Deficits in Schizophrenic https://ClinicalTrials.gov/show/NCT02128919 Completed Nathan Kline Institute for Psychiatric Research 2016-12-31
NCT02096068 Neuroprotection With Dexmedetomidine in Patients Undergoing Elective Cardiac or Abdominal Surgery (Neuprodex) https://ClinicalTrials.gov/show/NCT02096068 Completed Charite University, Berlin, Germany 2018-03-17
NCT01302314 Cognitive Rehabilitation in Patients With Spina Bifida https://ClinicalTrials.gov/show/NCT01302314 Completed Sunnaas Rehabilitation Hospital 2011-03-31
NCT02008357 Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss https://ClinicalTrials.gov/show/NCT02008357 Active, not recruiting Eli Lilly and Company 2022-07-22
NCT01983384 Anesthetic Depth and Postoperative Delirium Trial - 2 https://ClinicalTrials.gov/show/NCT01983384 Completed University of California, San Francisco 2017-10-31
NCT01951118 Olfactory Deficits and Donepezil Treatment in Cognitively Impaired Elderly https://ClinicalTrials.gov/show/NCT01951118 Completed New York State Psychiatric Institute 2019-05-31
NCT01946932 Cognitive Impairment Following Cardiac Arrest and Target Temperature Management https://ClinicalTrials.gov/show/NCT01946932 Completed Region Skane 2013-11-30
NCT01889602 Characterizing and Predicting Drug Effects on Cognition https://ClinicalTrials.gov/show/NCT01889602 Completed University of Minnesota 2016-08-31
NCT01881646 Postoperative Neuroinflammation and Cognitive Dysfunction After Abdominal Surgery https://ClinicalTrials.gov/show/NCT01881646 Completed Karolinska University Hospital 2016-02-29
NCT04210713 Neuroimmune Dysfunction in Alcohol Use Disorder https://ClinicalTrials.gov/show/NCT04210713 Recruiting University of Maryland, Baltimore 2022-08-31
NCT01763983 Effects of Cognitive Behavioural Therapy and Exercise on Stress and Cognitive Deficits in Multiple Sclerosis https://ClinicalTrials.gov/show/NCT01763983 Completed Sunnybrook Health Sciences Centre 2016-10-31
NCT01732653 A Treadmill Training Program Augmented by Virtual Reality to Decrease Fall Risk in Older Adults https://ClinicalTrials.gov/show/NCT01732653 Completed Tel-Aviv Sourasky Medical Center 2015-04-30
NCT01678755 A Phase 2 Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia https://ClinicalTrials.gov/show/NCT01678755 Completed AbbVie 2014-03-31
NCT01655680 A Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia https://ClinicalTrials.gov/show/NCT01655680 Completed AbbVie 2014-04-30
NCT01635348 Thinking, Walking Outcomes by Type of Exercise https://ClinicalTrials.gov/show/NCT01635348 Completed University of Pittsburgh 2013-05-31
NCT01561820 Mild Cognitive Impairment, Buddy Supported Exercise/ My Buddy Study https://ClinicalTrials.gov/show/NCT01561820 Completed Wake Forest University Health Sciences 2012-12-31
NCT01536977 Phase II Early Behavioral Intervention in BMT w/ Sleep Disturbance-Assess QOL+Fatigue+Cognitive f(x) https://ClinicalTrials.gov/show/NCT01536977 Completed Stanford University 2013-09-30
NCT01481961 Study of Repetitive Transcranial Magnetic Stimulation (rTMS) as add-on Treatment for Early Alzheimer’s Disease https://ClinicalTrials.gov/show/NCT01481961 Completed Centre Hospitalier Universitaire de Besancon 2012-05-31
NCT01466270 Study of Donepezil in Female Breast Cancer Survivors With Cognitive Dysfunction https://ClinicalTrials.gov/show/NCT01466270 Completed Wake Forest University Health Sciences 2013-10-31
NCT01428349 Matching Cognitive Remediation to Cognitive Deficits in Substance-Abusing Inmates https://ClinicalTrials.gov/show/NCT01428349 Completed University of Wisconsin, Madison 2013-05-31
NCT01394796 Egcg, a dyrk1a Inhibitor as Therapeutic Tool for Reversing Cognitive Deficits in Down Syndrome Individuals. https://ClinicalTrials.gov/show/NCT01394796 Completed Parc de Salut Mar 2011-02-28
NCT01346163 Add On Treatment for Cognitive Deficits in Schizophrenia https://ClinicalTrials.gov/show/NCT01346163 Completed University of Pennsylvania 2010-11-30
NCT01339195 Post-stroke Cognitive Impairment and Dementia https://ClinicalTrials.gov/show/NCT01339195 Completed Centre Hospitalier Universitaire, Amiens 2016-12-31
NCT04398355 A Clinical Trail of Traditional Chinese Medicine Rehabilitation for Stroke Lead to Dysphagia / Cognitive Disorder https://ClinicalTrials.gov/show/NCT04398355 Recruiting The Third Affiliated hospital of Zhejiang Chinese Medical University 2023-12-31
NCT04295681 Clinical Trial of Efficacy and Safety of MMH-MAP in the Treatment of Cognitive Disorders https://ClinicalTrials.gov/show/NCT04295681 Recruiting Materia Medica Holding 2022-12-31
NCT04291118 Assessing Improvement in Cognitive Deficit in CRS in Patients Treated With Medical Vs Surgical Management https://ClinicalTrials.gov/show/NCT04291118 Recruiting St. Paul’s Hospital, Canada 2021-09-01
NCT04289142 Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients https://ClinicalTrials.gov/show/NCT04289142 Recruiting Sunnybrook Health Sciences Centre 2026-03-11
NCT04251624 Investigating the Use of Goal Management Therapy in Improving Cognitive Functioning in Public Safety Personnel With PTSD https://ClinicalTrials.gov/show/NCT04251624 Recruiting Homewood Research Institute 2021-02-28
NCT04065061 Erinacine A-enriched Hericium Erinaceus Mycelia for Improvement of Recognition, Vision, and Functional MRI Alterations https://ClinicalTrials.gov/show/NCT04065061 Completed Chung Shan Medical University 2016-05-10
NCT04051528 Do Combinatorial Training Lead to Better Cognition and Daily Participation in TBI Persons With Cognitive Impairments https://ClinicalTrials.gov/show/NCT04051528 Recruiting Chang Gung Memorial Hospital 2021-07-31
NCT04049643 Hearing Aid and Individuals With Cognitive Disorders https://ClinicalTrials.gov/show/NCT04049643 Recruiting University of Iowa 2020-12-31
NCT04041999 Study of a Daily Cognition Training Program https://ClinicalTrials.gov/show/NCT04041999 Completed University of Salamanca 2019-12-31
NCT04019665 Self-screening of Cognitive Impairment in Primary Care https://ClinicalTrials.gov/show/NCT04019665 Recruiting Centre Hospitalier Universitaire, Amiens 2020-11-30
NCT03985540 Treating Cognitive Deficits in Traumatic Spinal Cord Injury (SCI) https://ClinicalTrials.gov/show/NCT03985540 Recruiting Kessler Foundation 2020-10-30
NCT03926351 High Dose Omega 3 in People at Risk for Dementia https://ClinicalTrials.gov/show/NCT03926351 Recruiting University Hospital, Akershus 2019-10-31
NCT03914313 Robotics Plus VR in Improving Cognition https://ClinicalTrials.gov/show/NCT03914313 Completed IRCCS Centro Neurolesi “Bonino-Pulejo” 2019-11-10
NCT03864965 Advance Care Planning in Cognitive Disorders Clinic https://ClinicalTrials.gov/show/NCT03864965 Recruiting University of Florida 2020-08-31
NCT03856502 Influence of Intrathecal Dexamethasone Administration for Proximal Femoral Fractures https://ClinicalTrials.gov/show/NCT03856502 Completed General Hospital Sveti Duh 2016-05-26
NCT03788330 Short-term Health Benefits of Using Fresh Air Filtration System in Classroom https://ClinicalTrials.gov/show/NCT03788330 Completed Fudan University 2019-01-20
NCT03720184 Haemo-autologous Antegrade Repriming (HAR) as Minimum Impact Perfusion Strategy for Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT03720184 Active, not recruiting Hospital Universitario Virgen de la Arrixaca 2019-09-01
NCT03696082 A Precision Rehabilitation Approach to Counteract Age-Related Cognitive Declines https://ClinicalTrials.gov/show/NCT03696082 Recruiting University of Pittsburgh 2020-12-31
NCT03695614 Cognitive Remediation Therapy for Participants With Late-Life Schizophrenia https://ClinicalTrials.gov/show/NCT03695614 Recruiting Centre for Addiction and Mental Health 2020-09-30
NCT04456777 Effect of Vortioxetine on Cognitive Symptoms in Patients With Schizophrenia https://ClinicalTrials.gov/show/NCT04456777 Recruiting Clinical Hospital Centre Zagreb 2022-07-01
NCT03623477 Can Cognitive Training Decrease Reactive Aggression? https://ClinicalTrials.gov/show/NCT03623477 Completed Weill Medical College of Cornell University 2019-10-25
NCT03528044 Emotional Regulation, Cognition, Impulsivity and Reward System in Obesity: A Prospective Study of Bariatric Surgery https://ClinicalTrials.gov/show/NCT03528044 Recruiting Koç University 2021-06-06
NCT03479970 Rehabilitation of Social Cognition in Subjects With Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03479970 Active, not recruiting Institut Guttmann 2021-01-02
NCT01186471 The Effect of Nicotine on Arousal, Cognition and Social Cognition in Schizophrenic Patients https://ClinicalTrials.gov/show/NCT01186471 Completed Janssen Pharmaceutica N.V., Belgium NA
NCT01184638 Long-term Outcome of General Anesthesia on Dysgnosia https://ClinicalTrials.gov/show/NCT01184638 Recruiting Nanjing Medical University 2020-08-31
NCT01181934 The Effect of Nicotine on Arousal, Cognition and Social Cognition in Young and Elderly Healthy Subjects. https://ClinicalTrials.gov/show/NCT01181934 Completed Janssen Pharmaceutica N.V., Belgium NA
NCT01095562 Safety and Efficacy Study for Cognitive Deficits in Adult Subjects With Schizophrenia https://ClinicalTrials.gov/show/NCT01095562 Completed AbbVie 2011-08-31
NCT01094145 Deep Brain Stimulation (DBS) of the Nucleus Basalis Meynert (NBM) to Treat Cognitive Deficits in Light to Moderate Alzheimer’s Disease https://ClinicalTrials.gov/show/NCT01094145 Completed University of Cologne 2013-01-31
NCT01077700 Efficacy and Safety Study for Cognitive Deficits in Adult Subjects With Schizophrenia https://ClinicalTrials.gov/show/NCT01077700 Completed AbbVie 2011-07-31
NCT01074619 Study on Cognitive Disorders of Multiple Sclerosis https://ClinicalTrials.gov/show/NCT01074619 Completed University Hospital, Caen 2011-03-31
NCT01040858 Cognitive Rehabilitation of Operations Iraqi Freedom and Enduring Freedom (OIF/OEF) Veterans With Cognitive Disorder https://ClinicalTrials.gov/show/NCT01040858 Completed VA Office of Research and Development 2013-05-31
NCT01032200 Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors https://ClinicalTrials.gov/show/NCT01032200 Completed Wake Forest University Health Sciences 2013-01-08
NCT03870893 Effects of Hippotherapy on Physical Fitness and Attention in Cerebral Palsy https://ClinicalTrials.gov/show/NCT03870893 Recruiting Samsung Medical Center 2020-02-28
NCT00974376 Gabapentin Treatment of Cannabis Dependence https://ClinicalTrials.gov/show/NCT00974376 Completed The Scripps Research Institute 2016-05-19
NCT00950586 Safety, Blood Levels, Drug Interaction and Effects of Repeated Doses of GSK1034702 https://ClinicalTrials.gov/show/NCT00950586 Completed GlaxoSmithKline 2009-12-24
NCT00937846 Brain Uptake of GSK1034702: a Positron Emission Tomography (PET) Scan Study https://ClinicalTrials.gov/show/NCT00937846 Completed GlaxoSmithKline 2009-08-28
NCT00895154 A Rehabilitation Program in Children With Sickle Cell Disease and Cognitive Deficits: a Pilot Study https://ClinicalTrials.gov/show/NCT00895154 Completed Washington University School of Medicine 2014-07-31
NCT00844974 Cognitive Deficits in Major Depressive Disorder and Bipolar Disorder, Depressed Type: Prevalence and Improvement With Treatment of Depressive Symptoms https://ClinicalTrials.gov/show/NCT00844974 Completed Massachusetts General Hospital 2012-12-31
NCT02360813 Cognitive Remediation Therapy Within a Secure Forensic Setting https://ClinicalTrials.gov/show/NCT02360813 Completed Central Mental Hospital 2017-01-31
NCT03538522 A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831 https://ClinicalTrials.gov/show/NCT03538522 Completed NeuroActiva, Inc. 2019-09-30
NCT00802919 Varenicline for Cognitive Deficits and Cigarette Smoking in Schizophrenia - Efficacy and Predictors https://ClinicalTrials.gov/show/NCT00802919 Completed Nathan Kline Institute for Psychiatric Research 2013-12-31
NCT02324153 Ramelteon in the Prevention of Post-operative Delirium https://ClinicalTrials.gov/show/NCT02324153 Completed Johns Hopkins University 2019-06-26
NCT03273439 A Study of rTMS for Cognitive Deficits in Chronic Patients With Schizophrenia https://ClinicalTrials.gov/show/NCT03273439 Completed Suzhou Psychiatric Hospital 2014-02-01
NCT02178995 Methylphenidate Treatment of Attention Deficits in Epilepsy https://ClinicalTrials.gov/show/NCT02178995 Completed Stanford University 2015-09-30
NCT00788918 Study of Cerebral Function in Patients With Chronic Hepatitis C Infection (HCV/CNS) https://ClinicalTrials.gov/show/NCT00788918 Completed University of Aarhus 2012-11-30
NCT00743405 Safety, Tolerability and Pharmacokinetics of GSK1034702 in Healthy Subjects https://ClinicalTrials.gov/show/NCT00743405 Completed GlaxoSmithKline 2008-12-15
NCT00702364 Efficacy Study of Strattera for Treating Attention Disorders in Traumatic Brain Injury (TBI) https://ClinicalTrials.gov/show/NCT00702364 Completed Craig Hospital 2012-03-31
NCT00695136 The Effect of Donepezil (Aricept(Registered Trademark)) on REM Sleep in Children With Autism https://ClinicalTrials.gov/show/NCT00695136 Completed National Institutes of Health Clinical Center (CC) 2011-01-31
NCT00658450 Rehabilitation Program for Cognitive Deficits in Ugandan Children After Cerebral Malaria https://ClinicalTrials.gov/show/NCT00658450 Completed Makerere University 2010-10-31
NCT00582491 Modafinil, Sleep, and Cognition in Cocaine Dependence https://ClinicalTrials.gov/show/NCT00582491 Completed Yale University 2009-02-28
NCT00567203 A Study Of Adjunctive Treatment Of Cognitive Deficits In Schizophrenia https://ClinicalTrials.gov/show/NCT00567203 Completed Pfizer 2008-05-31
NCT00564902 The Zeaxanthin and Visual Function Study https://ClinicalTrials.gov/show/NCT00564902 Completed Chrysantis, Inc. 2009-05-31
NCT00487942 Efficacy and Safety of Armodafinil as Adjunctive Therapy in Schizophrenic Adults With Cognitive Deficits https://ClinicalTrials.gov/show/NCT00487942 Completed Teva Pharmaceutical Industries 2007-12-31
NCT00463879 Galantamine for Cognitive Deficits in Schizophrenia https://ClinicalTrials.gov/show/NCT00463879 Completed Yale University NA
NCT00458094 Peer Support for Increasing Physical Activity in People With Serious Mental Illnesses https://ClinicalTrials.gov/show/NCT00458094 Completed Johns Hopkins University 2009-12-31
NCT00402311 The Effects and Cost-Effectiveness of an Integrated Multidisciplinary Approach for Psychogeriatric Patients https://ClinicalTrials.gov/show/NCT00402311 Completed Maastricht University Medical Center NA
NCT00400790 Organ Protection for Coronary Artery Bypass Graft (CABG): Propofol Versus Desflurane https://ClinicalTrials.gov/show/NCT00400790 Completed University of Melbourne 2010-01-31
NCT00300716 Trial of Memantine for Cognitive Impairment in Multiple Sclerosis https://ClinicalTrials.gov/show/NCT00300716 Completed Oregon Health and Science University 2009-01-31
NCT00267163 Brain Imaging and Mental Disorders of Aging Intervention https://ClinicalTrials.gov/show/NCT00267163 Completed National Institute on Aging (NIA) 2007-07-31
NCT02847403 Long-acting Exenatide and Cognitive Decline in Dysglycemic Patients https://ClinicalTrials.gov/show/NCT02847403 Recruiting Azienda Ospedaliero-Universitaria di Parma 2019-07-31
NCT00240695 A Follow-up Study to Assess Safety and Tolerability of Galantamine Treatment in Individuals With Mild Cognitive Impairment https://ClinicalTrials.gov/show/NCT00240695 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. NA
NCT00237809 D-Serine Treatment of Negative Symptoms and Cognitive Deficits in Schizophrenia https://ClinicalTrials.gov/show/NCT00237809 Completed Yale University 2010-12-31
NCT00219245 An Extension Study Evaluating the Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury (TBI) With Persistent Cognitive Deficits https://ClinicalTrials.gov/show/NCT00219245 Completed Novartis 2005-01-31
NCT00212147 Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly https://ClinicalTrials.gov/show/NCT00212147 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2008-08-31
NCT00189215 Long-Term Cognitive Decline After Coronary Artery Bypass Grafting: is Off-Pump Surgery Beneficial? https://ClinicalTrials.gov/show/NCT00189215 Completed UMC Utrecht NA
NCT00161031 Atomoxetine as an Adjunct to Novel Antipsychotic Medication in the Treatment of Cognitive Deficits of Schizophrenia https://ClinicalTrials.gov/show/NCT00161031 Completed University of Maryland, Baltimore 2006-12-31
NCT00138905 Experimental Study of Mobile Base Station Related Radio-Frequency Electromagnetic Radiation https://ClinicalTrials.gov/show/NCT00138905 Completed University of Aarhus NA
NCT00105378 Dutch EASYcare Study https://ClinicalTrials.gov/show/NCT00105378 Completed Radboud University NA
NCT00096863 The MIND Study: Modifying the INcidence of Delirium https://ClinicalTrials.gov/show/NCT00096863 Completed Vanderbilt University 2007-07-31
NCT00052091 Therapy for Depressed Elders With Thought Problems https://ClinicalTrials.gov/show/NCT00052091 Completed University of Washington 2008-03-31
NCT00047697 Donepezil HCl & Cognitive Deficits in Autism https://ClinicalTrials.gov/show/NCT00047697 Completed University of Pittsburgh 2006-08-31
NCT00042172 Treatment for Early Memory Loss https://ClinicalTrials.gov/show/NCT00042172 Completed University of Iowa 2004-09-30
NCT00027040 A Study of Decreased Mental Function Associated With HIV https://ClinicalTrials.gov/show/NCT00027040 Completed National Institute of Allergy and Infectious Diseases (NIAID) NA
NCT00529581 A Study of C105 on Cognitive Dysfunction in Persons With Multiple Sclerosis https://ClinicalTrials.gov/show/NCT00529581 Completed Cognition Pharmaceuticals, LLC 2008-03-31
NCT00013585 Safety and Effectiveness of the Selegiline “Patch” for Decreased Mental Function in HIV Patients https://ClinicalTrials.gov/show/NCT00013585 Completed National Institute of Allergy and Infectious Diseases (NIAID) NA
NCT00002154 A Study of Thioctic Acid and Deprenyl in HIV-Infected Patients With Dementia https://ClinicalTrials.gov/show/NCT00002154 Completed NIH AIDS Clinical Trials Information Service NA
NCT00002148 Parallel Group, Placebo-Controlled, Tolerability, Safety, and Efficacy Study of OPC-14117 in HIV Dementia https://ClinicalTrials.gov/show/NCT00002148 Completed NIH AIDS Clinical Trials Information Service NA
NCT00000393 A Phase I Trial of Peptide T: Efficacy for the Neuropsychiatric Complications of Acquired Immunodeficiency Syndrome (AIDS). https://ClinicalTrials.gov/show/NCT00000393 Completed National Institute of Mental Health (NIMH) 1990-01-31
NCT00000392 Phase II Study of the Efficacy of Peptide T in HIV-Positive Individuals With Cognitive Impairment. https://ClinicalTrials.gov/show/NCT00000392 Completed National Institute of Mental Health (NIMH) 1996-08-31
NCT00000174 Investigation Into Delay to Diagnosis of Alzheimer’s Disease With Exelon (InDDEx) https://ClinicalTrials.gov/show/NCT00000174 Completed National Institute on Aging (NIA) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03360838 Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool https://ClinicalTrials.gov/show/NCT03360838 Recruiting University Hospital, Basel, Switzerland 2021-03-31
NCT03279835 Evaluation of a Short Version Computerized Test for Processing Speed to Detect Cognitive Disorders in HIV+ Patients https://ClinicalTrials.gov/show/NCT03279835 Completed Centre Hospitalier Universitaire de Nice 2018-10-30
NCT03252054 Memory and Attention Disorders and Malnutrition in Hospital Setting https://ClinicalTrials.gov/show/NCT03252054 Completed Tampere University Hospital 2016-12-31
NCT03246269 Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA) https://ClinicalTrials.gov/show/NCT03246269 Completed University Hospital, Basel, Switzerland 2017-04-30
NCT03032471 Swiss SOS MoCA - DCI Study https://ClinicalTrials.gov/show/NCT03032471 Recruiting Swiss SOS Study Group 2020-07-31
NCT02964221 Cognitive Changes After Major Joint Replacement https://ClinicalTrials.gov/show/NCT02964221 Completed Sunnybrook Health Sciences Centre 2017-05-01
NCT02828813 Neural Mechanisms of Motor and Cognitive Networks https://ClinicalTrials.gov/show/NCT02828813 Completed National Research Center for Rehabilitation Technical Aids 2019-02-28
NCT02778438 A Validation Study of the Novel Application of Telehealth in Clinical Drug Development in Subjects With Mild Cognitive Deficits https://ClinicalTrials.gov/show/NCT02778438 Completed Quintiles, Inc. 2016-08-31
NCT02753036 Chemotherapy-induced Cognitive Alterations in Recruits With Ovarian and Breast Cancer https://ClinicalTrials.gov/show/NCT02753036 Recruiting Charite University, Berlin, Germany 2019-07-31
NCT02488720 Longitudinal Evaluation of Amyloid Risk and Neurodegeneration - the LEARN Study https://ClinicalTrials.gov/show/NCT02488720 Active, not recruiting University of Southern California 2022-07-31
NCT02421497 MRI Technical Development and Applications in Kidney Disease https://ClinicalTrials.gov/show/NCT02421497 Recruiting University of Minnesota 2022-12-30
NCT02321475 EGb 761® (Tanakan®) Effectiveness in the Treatment of Patients of Middle Age and Younger With Psycho-emotional Symptoms, Added to Cognitive Disorders https://ClinicalTrials.gov/show/NCT02321475 Completed Ipsen 2015-04-30
NCT02118571 Schizophrenia Cognition Scale Development https://ClinicalTrials.gov/show/NCT02118571 Completed HealthCore-NERI 2016-07-31
NCT02058043 Study of MRI 3Tesla Infusion Without Arterial Spin Labeling Injection (ASL) in Cognitive Atypical and Comparison to the FDG-PET https://ClinicalTrials.gov/show/NCT02058043 Completed Rennes University Hospital 2017-12-31
NCT01772095 ADVANCE Study: Alzheimer Disease eVAluation iN Clinical PracticE https://ClinicalTrials.gov/show/NCT01772095 Completed Elpen Pharmaceutical Co. Inc. 2013-11-30
NCT01481246 Neurocognitive Study for the Aging https://ClinicalTrials.gov/show/NCT01481246 Recruiting University of Cyprus 2022-03-31
NCT01359215 Childhood Anesthesia and Cognitive Function https://ClinicalTrials.gov/show/NCT01359215 Completed University of California, San Francisco 2012-05-31
NCT04204239 Validation Study SCOBES-AR https://ClinicalTrials.gov/show/NCT04204239 Recruiting FH Joanneum Gesellschaft mbH 2020-06-30
NCT04169633 Spanish Adaptation and Validation of the Everyday Cognition Battery (ECB). https://ClinicalTrials.gov/show/NCT04169633 Recruiting University of Salamanca 2020-12-31
NCT04111211 Long-term Follow-up of Cognitive and Functional Evolutions of Persons With Isolated Cognitive Complaints or Mild Cognitive Deficits https://ClinicalTrials.gov/show/NCT04111211 Recruiting University Hospital, Bordeaux 2024-12-31
NCT03723356 Linking Cognitive Functioning to Multimodal Imaging in Multiple Sclerosis (MS) https://ClinicalTrials.gov/show/NCT03723356 Recruiting NYU Langone Health 2021-12-13
NCT03679026 The “Motoric Cognitive Risk” Syndrome in the Canadian Population https://ClinicalTrials.gov/show/NCT03679026 Recruiting Jewish General Hospital 2020-08-21
NCT03657745 Alzheimer’s Disease Treatment With Combination of 40Hz Light and Cognitive Therapy https://ClinicalTrials.gov/show/NCT03657745 Recruiting Alzheimer’s Light LLC 2023-12-31
NCT03633253 The “Motoric Cognitive Risk” Syndrome in the Quebec Population https://ClinicalTrials.gov/show/NCT03633253 Active, not recruiting Jewish General Hospital 2020-12-07
NCT03544801 Renji Cerebral Small Vessel Disease Corhort Study https://ClinicalTrials.gov/show/NCT03544801 Recruiting RenJi Hospital 2020-12-30
NCT03543371 Neuropsychological Outcome After Cardiac Arrest https://ClinicalTrials.gov/show/NCT03543371 Recruiting Region Skane 2021-07-31
NCT03540433 International Observational Study on Perioperative Cognitive Trajectories (POCD Census International/PCI) https://ClinicalTrials.gov/show/NCT03540433 Recruiting Charite University, Berlin, Germany 2022-01-31
NCT01150071 Growth, Health and Development in Children Born Extremely Preterm https://ClinicalTrials.gov/show/NCT01150071 Completed University of Bergen 2012-12-31
NCT01049308 Cognitive Problems in Veterans With Heart Failure https://ClinicalTrials.gov/show/NCT01049308 Completed VA Office of Research and Development 2011-04-30
NCT00911690 Establishment of a Bank of Biospecimens for Future Research on Age-related Cognitive Disorders https://ClinicalTrials.gov/show/NCT00911690 Completed William Beaumont Hospitals 2016-03-31
NCT04370028 Study on Efficacy and Safety of Divaza in Patients With Chronic Cerebral Ischemia and Cognitive Disorders https://ClinicalTrials.gov/show/NCT04370028 Completed Materia Medica Holding 2017-01-31
NCT03286439 Recovery After Medical or Surgical Treatment https://ClinicalTrials.gov/show/NCT03286439 Completed Zealand University Hospital 2018-07-06
NCT00004571 Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy Volunteers https://ClinicalTrials.gov/show/NCT00004571 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT04053556 Cognitive Performance After a Night Shift in Internal Medicine Residents https://ClinicalTrials.gov/show/NCT04053556 Completed Hospital Italiano de Buenos Aires 2019-08-08
NCT03938870 CNS Tau Kinetics in Healthy Aging and Alzheimer’s Disease https://ClinicalTrials.gov/show/NCT03938870 Recruiting Washington University School of Medicine 2021-03-31
NCT00512200 Postoperative Cognitive Dysfunction in Geriatric Patients https://ClinicalTrials.gov/show/NCT00512200 Completed University Hospital, Basel, Switzerland 2012-02-29
NCT00392795 The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors https://ClinicalTrials.gov/show/NCT00392795 Active, not recruiting Vanderbilt University Medical Center 2010-12-31
NCT00001363 PET Scan to Map the Areas of the Brain Involved in Planning https://ClinicalTrials.gov/show/NCT00001363 Completed National Institutes of Health Clinical Center (CC) NA
NCT00043238 Mohawk Culture, Behavior, Toxicant Exposure and Health https://ClinicalTrials.gov/show/NCT00043238 Completed National Institute of Environmental Health Sciences (NIEHS) 2005-07-31
NCT00294307 Enhancing Care Coordination: Hospital to Home for Cognitively Impaired Older Adults and Their Caregivers https://ClinicalTrials.gov/show/NCT00294307 Completed University of Pennsylvania 2010-07-31
NCT00001103 HIV Levels in Cerebrospinal Fluid and Brain Function in Patients Receiving Anti-HIV Drugs https://ClinicalTrials.gov/show/NCT00001103 Completed National Institute of Allergy and Infectious Diseases (NIAID) NA
NCT00021866 Developmental Effects On Children Of Women Who Take Antiepileptic Drugs During Pregnancy https://ClinicalTrials.gov/show/NCT00021866 Completed Emory University 2010-08-31
NCT00001950 The Development of Categorization https://ClinicalTrials.gov/show/NCT00001950 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02918539 Registry of Amyloid Positive Patients for Alzheimer’s Disease Drug Research Trials https://ClinicalTrials.gov/show/NCT02918539 Completed Avid Radiopharmaceuticals 2017-10-18
NCT04096261 The Importance of Sleep Quality and the Blood-brain Barrier in Cognitive Disorders and Alzheimer’s Disease https://ClinicalTrials.gov/show/NCT04096261 Recruiting Charite University, Berlin, Germany 2019-12-31
NCT04085107 The Moderating Roles of Social Support, Coping Resources and Personality and Mediating Role of Self-esteem on the Impact of Cognitive Deficit on Neuropsychiatric Symptoms Among Persons With Mild Cognitive Impairment: A Mixed-method Sequential Explanatory Design https://ClinicalTrials.gov/show/NCT04085107 Recruiting Chinese University of Hong Kong 2020-01-31
NCT03477578 Freezing of Gait and Cognition https://ClinicalTrials.gov/show/NCT03477578 Completed Ospedale Generale Di Zona Moriggia-Pelascini 2018-02-28